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Ggt1-cre

Web021504 B6.Cg-Tg(Vil1-cre)1000Gum/J These Vil1-cre mice express Cre recombinase in villus and crypt epithelial cells of the small and large intestines and may be useful in studies of intestinal organogenesis. In addition, Vil1-cre transgenic mice from founder line 1000 are reported to be absent of Cre recombinase activity in gonads. WebNov 1, 2024 · Section snippets Mouse lines used and study approval. Fan1 loxP/loxP mice were bred with γGt1-Cre mice (#012841, Tg(Ggt1-cre)M3Egn/J) 28 to generate proximal tubule–specific Fan1 KO. γGt1-Cre expression in the proximal tubule was demonstrated by crossing γGt1-Cre mice with NuTRAP mice (Jackson Laboratories #029899, B6;129S6 …

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WebFeb 5, 2012 · Here we show that the BMP receptor activin-like kinase 3 (Alk3) is elevated early in diseased kidneys after injury. We also found that its deletion in the tubular epithelium leads to enhanced TGF-β1-Smad family member 3 (Smad3) signaling, epithelial damage and fibrosis, suggesting a protective role for Alk3-mediated signaling in the kidney. WebTg (Ggt1-cre/ERT2)1Pepe. Mutation details : 411 bp of the mouse Ggt1 promoter was used to drive expression of an inducible cre/ERT2fusion in the proximal tubule of the kidney. One founder was created with 50 to 70 copies of the transgene integrated into the X chromosome. ( J:137094 ) how to mod red dead redemption 2 https://glynnisbaby.com

GGT-Cre mice for tissue-specific gene ablation in proximal kidney ...

Webline expressing Cre recombinase under the control of the Ggt1 promoter (28). As indicated in Figure 1A, to generate a renal prox-imal tubule–specific -KO mouse line (Pten ptKO), we crossed Pten this Ggt1-Cre mouse with Pten exon 5–floxed mice (Ptenfl/fl); exon 5 encodes the essential phosphatase core domain of the PTEN protein (27). WebOct 12, 2024 · floxed mice (stock no. 013106, Jackson Laboratory) with Ggt1-Cre mice (stock no. 012841, Jackson Laboratory). We obtained mT/mG mice that express the cell membrane-targeted (mT), two-color fluores-cent Cre reporter allele from Jackson Laboratories (stock no. 007676). mT/mG mice were bred with the Ggt1-Cre strain to … Web012841 STOCK Tg(Ggt1-cre)M3Egn/J These GT.cre transgenic mice express Cre recombinase in cortical tubular epithelium of the kidney and may be useful for generating … mum and daughter matching clothes uk

肾小管组织特异性CRE 工具鼠 - 北京 - 百奥赛图 - 豆丁网

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Ggt1-cre

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WebGgt1 tm1a(EUCOMM)Wtsi: Name: gamma-glutamyltransferase 1; targeted mutation 1a, Wellcome Trust Sanger Institute: MGI ID: MGI:4432621: Gene: Ggt1 Location: Chr10:75397438-75422034 bp, + strand Genetic Position: Chr10, 38.55 cM Alliance: Ggt1 tm1a(EUCOMM)Wtsi page IMPC: Ggt1 gene page WebFigure Legend Snippet: ( A ) Targeting construct was designed for integration into the ROSA26 region, and the expression cassette was designed with the CAG promoter-floxed stop codon-Trip13 cDNA-T2A-EGFP-polyA. 2A, protease cleavage site ( Trip13 cDNA was FLAG tagged at the 3′ end); CAG, CMV-IE enhancer/chicken β-actin/rabbit β-globin. ( B ) …

Ggt1-cre

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WebMar 13, 2024 · The Ggt1-Cre mice have a mix of BALB/cJ and C57BL/6 background. Animal models of acute kidney injury Given that AKI is associated with distinct disease conditions, multiple mouse models have been developed. 20 Ischemia, cisplatin, and rhabdomyolysis-associated AKI was triggered in male mice aged 8–12 weeks using … WebTo breed corin kcKO mice, Cor flox mice were bred with Ggt1-Cre mice (Tg(Ggt1-cre)M3Egn/J, Jackson Laboratory, Bar Harbor, ME, USA), expressing renal Cre under the Ggt1 promoter [84,85] . The mice were crossed (>10 generations) into the C57BL/6J background. WT C57BL/6J mice were used as controls.

WebNov 9, 2024 · Ggt1-Cre mice were crossed with Sox9-floxed mice to generate RTEC-specific knockout mice. Eight- to ten-wk-old male littermate control and cyclin-dependent kinase-like 5 (Cdkl5) conditional knockout male mice (indicated by Cdkl5 PT−/y ) were challenged with rhabdomyolysis (Rhabdo; 7.5 mL/kg of 50% glycerol in both hindleg … http://www.informatics.jax.org/recombinase/specificity?id=MGI:3811269&system=renal+%26+urinary+system

http://www.informatics.jax.org/allele/allgenoviews/MGI:3811269 WebJul 5, 2024 · In Vgat-Cre neg lamina II neurons, CNO produced facilitation of A fibre-mediated polysynaptic excitatory responses, an effect that required N-methyl-D-aspartate (NMDA) receptor activation. The CNO-induced nocifensive behaviours were also reduced by NMDA receptor antagonism. Moreover, these nocifensive behaviours were suppressed …

WebMar 1, 2024 · wcn23-0488 decoy receptor 2 mediates tubular maladaptive repair by regulating ketogenesis after acute kidney injury

mum and daughter matching shirtsWebApr 27, 2024 · Proximal tubule-specific loss of Sirt6 increases UUO-induced extracellular matrix deposition. (A) Representative sections of kidneys from sham-and UUO-operated Sirt6 flox/flox ; Ggt1-Cre -(WT) and ... how to mod red dead 2 pcWebApr 21, 2024 · l Ggt1-Cre mice were crossed with ROSA mT/mG mice to generate transgenic mice that express membrane-localized EGFP in renal tubular epithelial cells. … mum and daughter necklace setWebApr 5, 2014 · 目前已有的PEPCK-cre工具鼠仅有Hprttm1(Pck1-cre)Vhh变型启动子使肝中cre表达降低60%，而肝中cre表达提高10倍。 同时需注意此工具鼠中同时敲除了Hprt基 … mum and daughter pebble artWebMay 15, 2024 · Ggt1-Cre mice were provided by Eric Neilson, Northwestern University (Chicago, IL), and described previously . The Ggt1 promoter is predominantly expressed … mum and daughter pictureshttp://www.informatics.jax.org/allele/MGI:3798834 mum and daughter matching outfitsWebFeb 6, 2024 · Homozygous CrATloxP female mice (C57BL/6J) were bred to male γ-glutamyl transferase Cre mice (Tg-(Ggt1-cre)M3Egn/J, mixed Balb/cJ/C57BL/6 background; The … mum and daughter yoga classes near me