WebFeb 25, 2015 · Additionally, mutations in HER2 have been described in a small subset of cancers of the breast, lung, ovary, and colon . Anecdotal reports of patients with diverse cancers and HER2 amplification or mutation responding to anti-HER2 agents have been published [ 15 – 18 ], implying a potential role for anti-HER2 agents outside of breast and … WebApr 14, 2024 · C-X-C motif chemokine ligand 1 (CXCL1) is a member of the CXC chemokine subfamily and a ligand for CXCR2. Its main function in the immune system is the chemoattraction of neutrophils. However, there is a lack of comprehensive reviews summarizing the significance of CXCL1 in cancer processes. To fill this gap, this work …
The prognostic value of HER2 in ovarian cancer: A meta-analysis …
WebSep 4, 2013 · A panel of 32 “ovarian cancer” cell lines has been classified into histotypes using a combination of mutation profiles ... McAlpine JN, Wiegand KC, Vang R, Ronnett BM, Adamiak A, et al. (2009) HER2 overexpression and amplification is present in a subset of ovarian mucinous carcinomas and can be targeted with trastuzumab therapy ... WebYet another possible explanation of the variable results of anti-HER2 therapy in endometrial and ovarian carcinoma is the mechanism leading to HER2 amplification. The amplification ratios of HER2-positive tumours in our study were generally lower than in breast cancer (25–29% of cases with HER2/CEP17 ratio >5.0, versus >50% in breast cancer). euphoria on neon
American Association for Cancer Research
WebOvarian cancer is a group of diseases that originates in the ovaries, or in the related areas of the fallopian tubes and the peritoneum. Women have two ovaries that are located in the … WebApr 11, 2024 · Most ovarian cancers have several acquired mutations. Research has suggested that tests to identify acquired mutations in ovarian cancers, like the TP53 … WebOct 10, 2016 · HER2 targeted delivery of ovarian cancer therapy has been beneficial for some patients, although, its efficacy is yet to be confirmed in large populations. We … euphoria outfits fashion nova