Serine/threonine-protein kinase 6
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Serine/threonine-protein kinase 6
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Web4 Apr 2024 · Gene ID: 7443, updated on 18-Oct-2024 Summary This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. This gene is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, thymus, fetal liver, and carcinomas.
Aurora kinase A also known as serine/threonine-protein kinase 6 is an enzyme that in humans is encoded by the AURKA gene. Aurora A is a member of a family of mitotic serine/threonine kinases. It is implicated with important processes during mitosis and meiosis whose proper function is integral for healthy cell … See more The aurora kinases were first identified in 1990 during a cDNA screen of Xenopus eggs. The kinase discovered, Eg2, is now referred to as Aurora A. However, Aurora A's meiotic and mitotic significance was not recognized until … See more The human genome contains three members of the aurora kinase family: Aurora kinase A, Aurora kinase B and Aurora C kinase. The Xenopus, Drosophila, and See more During mitosis, a mitotic spindle is assembled by using microtubules to tether together the mother centrosome to its daughter. The resulting mitotic spindle is then used to propel apart the sister chromosomes into what will become the two new daughter … See more Aurora A dysregulation has been associated with high occurrence of cancer. For example, one study showed over-expression of Aurora A in 94 percent of the invasive tissue growth in breast cancer, while surrounding, healthy tissues had normal levels of … See more Aurora A localizes next to the centrosome late in the G1 phase and early in the S phase. As the cell cycle progresses, concentrations of … See more Aurora A phosphorylation directs the cytoplasmic polyadenylation translation of mRNA's, like the MAP kinase kinase kinase protein MOS, that are vital to the completion of … See more Aurora A is not only implicated with the translation of MOS during meiosis but also in the polyadenylation and subsequent translation of neural mRNAs whose protein products are … See more WebIntrinsic and acquired resistance to chemotherapy is the fundamental reason for treatment failure for many cancer patients. The identification of molecular mechanisms involved in drug resistance or sensitization is imperative. Here we report that
Web28 Jun 2024 · Lapatinib is a reversible and specific tyrosine kinases receptor inhibitor of ErbB1 and ErbB2. Besides, it possesses high affinity with K app s of 3 nM and 13 nM for ErbB1 and ErbB2, respectively. According to kinds of research, this drug has high antiproliferative activity against HER2-positive breast cancer cells. WebGene ID: 122562920, updated on 6-Nov-2024. Summary Other designations. serine/threonine-protein kinase TBK1-like
Webwo2024055731 - inhibitors of serine/threonine protein kinase stk3 or stk4 and uses thereof Publication Number WO/2024/055731 Publication Date 06.04.2024
Web8 Dec 2024 · TSSK6 testis specific serine kinase 6 Gene ID: 83983, updated on 8-Dec-2024 Gene type: protein coding Also known as: CT72; SSTK; TSSK4; FKSG82. See all available … coty for youWeb8 Feb 2024 · The CBL-Interacting Protein Kinase NtCIPK23 Positively Regulates Seed Germination and Early Seedling Development in Tobacco ( Nicotiana tabacum L.) The CBL … coty fosterWebwo2024055731 - inhibitors of serine/threonine protein kinase stk3 or stk4 and uses thereof Publication Number WO/2024/055731 Publication Date 06.04.2024 brecksville recreationWebThis work provides a map of the structural elements relevant for the design of more selective ATP-competitive MTPK inhibitors, and suggests schemes suitable for a major understanding of these proteins as antituberculotic targets. In the last decades, human protein kinases (PKs) have been relevant as targets in the development of novel therapies … coty flores guatemalaWeb6 Jul 2024 · Akt/PKB (Protein kinase B), usually called Akt, is a serine/threonine protein kinase with antiapoptotic activity.In addition, Akt consists of three isoforms: PKBα/Akt1, PKBβ/Akt2 and PKBγ/Akt3. Catalytically active Akt regulates the function of numerous substrates involved in cell survival, growth, proliferation, metabolism and protein synthesis. coty france sasWebThe serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. coty foundary. st louis moWebProtein Serine-Threonine Kinaseの意味や使い方 *** シソーラス 共起表現 Scholar, Entrez, Google, WikiPedia (酵素)タンパク質セリンスレオニンキナーゼ, タンパク質セリントレオニンキナーゼ関連語protein... - 約1456万語ある英和辞典・和英辞典。発音・イディオムも分か … brecksville reservation playground