Trim37 function
WebOct 9, 2016 · The TRIM family is known to be implicated in multiple cellular functions, including antiviral activity. However, it is presently unknown whether TRIM32 of common carp (Cyprinus carpio) has the antiviral effect. ... TRIM37 was incorporated into HIV-1 particles and its expression could severely diminish viral DNA synthesis . WebJun 12, 2024 · In this study, we attempted to investigate the function of tripartite motif-containing protein 37 (TRIM37) in GC cell lines in order to propose a new therapy for GC. …
Trim37 function
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WebBrowse Rare Disease Information. The table below displays a list of all rare diseases contained within RARe-SOURCE™, their gene associations, links to related features within RARe-SOURCE™ and links to external data sources. WebNov 15, 2024 · In this study, we unveiled a novel function of TRIM37 in regulating nuclear-to-cytoplasmic NF-κB signaling. We found that, upon genotoxic stimulation, TRIM37 rapidly translocated into the nucleus where it interacted directly with TRAF6 to catalyze monoubiquitination of NEMO at K309.
WebAug 21, 2024 · TRIM37 depletion increases basal autophagic flux. To explore how cells respond to the stresses caused by the loss of TRIM37 functions, we examined the … WebRemoves all spaces from text except for single spaces between words. Use TRIM on text that you have received from another application that may have irregular spacing. …
WebFurthermore, TRIM37 positively mediated the translocation of NF-κB to nuclear. It negatively regulated its ubiquitination in foam cells after interacting with TRAF2. Importantly, MYJ profoundly suppressed the function of TRIM37 in foam … WebJun 27, 2024 · A number of centrosome-related TRIM37 functions have been described. In the absence of TRIM37, a collection of centriole proteins such as CNTROB, PLK4, CETN1/2, CP110 accumulate to form aberrant assemblies referred to as condensates or ‘Cenpas’ (centriolar protein assemblies) (Balestra et al., 2024; Meitinger et al., 2024).
WebNov 24, 2014 · The RING finger protein TRIM37 is encoded by a gene that is amplified in certain breast cancers, but its function is unknown; here, it is shown to mono-ubiquitinate …
WebBCL6 function is also impaired by acetylation, which triggers BCL6 dissociation from corepressor complexes (Bereshchenko et al., 2002). Interestingly, acetylation has a negative effect on BCL6 activity while it positively affects the function of TP53, one of the well-characterized BCL6 targets, suggesting a coordinated action between functional silencing … huayi power washerWebThe TRIM37 (also known as MUL) gene is located in the 17q23 chromosomal region, which is amplified in up to ~40% of breast cancers1. TRIM37 contains a RING finger domain, a hallmark of E3 ... huayi secondary school cca timingWebJun 4, 2024 · The protein levels in NF-kB signaling was estimated by western blotting and immunoprecipitation assays were applied to demonstrate the direct interaction between … huayi spaceWebJun 27, 2024 · TRIM37 gene mutations cause mulibrey (muscle-liver-brain-eye) nanism, a severe growth disorder with prenatal onset. Although TRIM37 depletion normally induces apoptosis, patients with TRIM37 mutations have a high risk of developing tumors, suggesting that there may be an alternative pro-survival mechanism for TRIM37-deficient … huayi semiconductorWebDevelopmental and speech delay due to SOX5 deficiency is a rare genetic syndromic intellectual disability characterized by mild to severe global developmental delay, intellectual disability and behavioral abnormalities, hypotonia, strabismus, optic nerve hypoplasia and mild facial dysmorphic features (down slanting palpebral fissures, frontal bossing, … huayi precision metalWebNov 7, 2015 · : NA/NaN/Inf in foreign function call (arg 1) In addition: There were 28 warnings (use warnings() to see them) Warning messages: 1: In data.matrix(x) : NAs introduced by coercion 2: In data.matrix(x) : NAs introduced by coercion 3: In data.matrix(x) : NAs introduced by coercion 4: In data.matrix(x) : NAs introduced by coercion huayi plasticWebMutations in this gene are associated with mulibrey (muscle-liver-brain-eye) nanism, an autosomal recessive disorder that involves several tissues of mesodermal origin. TRIM37 localizes in peroxisomal membranes, and has been implicated in human peroxisomal biogenesis disorders. [provided by RefSeq, Jul 2024] ... hogan\\u0027s well repair